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Programmes

Next Generation Sequencing

Summer School of , 5 ECTS
Agriculture and environment Mathematics, natural- and computer science

Institution Aarhus University (AU)
Campus Aarhus
Duration 1 week
Tuition per term (Non-EU/EAA/CH) 1303 EUR
Tuition per term (EU/EAA/CH) 140 EUR
Website http://www.au.dk/en/summeruniversity/courses/next-generation-sequencing/

Description

The course will start with an overview of current NGS technologies and directions in which these are currently progressing. Methods for assembling genomes from NGS data using either a reference genome or de novo assembly will be presented together with some emphasis on assessing NGS data quality (Quality control, accuracy of base calling). The course will then offer an overview of the range of biological/biomedical questions that these new types of data can help to address. This includes: 
  • The use of NGS resequencing of closely related genomes for detecting mutations. This includes the characterization of somatic mutations in cancer tissues, the de novo mutation spectrum in eukaryotic genomes, and the detection of mutations underlying phenotypic changes in experimental or natural populations.
  • Combining NGS with methods aimed at reducing genome complexity such as exome resequencing in complex genomes.
  • The use of resequencing of a large number of individuals for Single Nucleotide Polymorphism (SNPs) and Copy number variation detection.
  • Application of NGS in Transcriptomics, Epigenomics and Chromatin structure studies. Environmental/Meta-genomics studies probing the bacterial/viral diversity of understudied biomes.
  • Comparative and evolutionary genomics.
To allow hands-on data analysis training, the course includes the following computer exercises, which can be completed using either your own or example data: 
  • Introduction to Galaxy, GATK and Samtools.
  • Grooming of reads.
  • Mapping of Illumina reads to reference.
  • SNP/indel calling, filtering and annotation.
  • Gene models and transcript quantification.

About the Degree

This is a summer course that counts 5 or 10 ECTS. 

Admission

  • You must be enrolled in a university programme at the time of the AU Summer University
  • If you are applying for admission to AU Summer University courses at the Master level, you must hold a relevant Bachelor's degree (or as a minimum 180 ECTS in your study programme
  • The application deadline is March 15th

Tuition

The tuition fee varies from course to course. Find the price on the individual course page. Find more information here http://www.au.dk/en/summeruniversity/tuitionfeeandparticipationfee/

For Further Information

You can find more information on the programme here www.au.dk/summeruniversity
If you have any questions regarding the programme please write summeruniversity@au.dk


Application date
Mar 15
Start date
Jun 20

Aarhus

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